BIOINFORMATICS SEMINAR SERIES California State University, San Bernardino Summer 2007 Fellowship at the Center for Bio-Image Informatics University of California, Santa Barbara 11 January 2008 Fri, JB 389/391 10:00 10:30 am, SADOT BANUET TITLE The Online Connection of Biological Databases ABSTRACT Bisquick is a biological image database that stores thousands of images from biological samples, developed by the bioinformatics center at UCSB. Researchers currently use the database for storage, manipulation, and analysis of image data sets. Our project goal is to expand the utility of the image database to link images, and image tags, seamlessly with numerous, powerful, existing scientific databases. In a single feature or tag-based query, the user can retrieve research-relevant information in multiple media forms, such as gene sequence, protein structure or primary literature, each parsed from independent sources. 10:30 11:00 am, STEVEN M. PARKER TITLE Tools for Microtubule Dynamics Analysis I ABSTRACT The goal of the project is to build a graphical user interface that provides a biological user the tools necessary to perform semi-automated tracking of microtubule tip distances. We develop a faster and more accurate software comparing to currently used commercial software such as RTM software. 11:00 11:30 am, JOSE FREIRE TITLE Evaluating the Performance of Microtubule Tracing and Retinal Layer Image Segmentation Algorithms ABSTRACT Two evaluation methodologies are proposed. (1) Two measures to evaluate retinal layer segmentation (2) An overall evaluation metric for microtubule tracing. In the retinal layer segmentation a weighted F-Measure is used to account for layer segmentation error and Fast Marching is used to efficiently calculate distance errors. The overall evaluation metric for microtubule tracing takes into account tip distance, trace distance, and length differences.